[Objective] The objective of this paper was to screen out suitable high- yielding cultivars and to understand the current yield performance of wheat in Anhui Province. In addition, the influencing factors on wheat yield were discussed to es- tablish suitable cultural practice. [Method] Main popularized cultivars and some new strains of wheat were selected as matedals and planted in the Funan Farm and Longkang Farm in 2009-2011. The yield stability and influencing factors on yield of wheat were discussed. [Resalt] In Anhui Province, the weather had a great influence on wheat yield, resulting in significant differences in wheat yield among different years. Drought was the main factor restricting the yield. [Conclusion] (1) It was easy to achieve high yield when the three influencing factors on wheat yield were coordi- nated. (2) The occurred drought disaster in 20tl was the main factor limiting the 1 000- grain weight and final yield of wheat. (3) Different cultivars showed different yield stabilities. Among the test wheat cultivars, two cultivars (Wanke 06290 and Yannong 19) showed good yield stability, while Xinfumai No.1 showed higher yield. (4) The three influencing factors played different roles in different cultivars. In the promotion process, the characteristics of wheat cultivars should be fully understood. To achieve high yield, integrating cultural practices is a necessity.