An optimal resource dispatching method is proposed to solve the multiple-response problem under the conditions of potential incidents on freeway networks.Travel time of the response vehicle is selected instead of route distance as the weight to reflect the impact of traffic conditions on the decisions of rescue resources.According to the characteristics of different types of rescue vehicles the dispatching decision-making time is revised to show the heterogeneity among different rescue vehicle dispatching modes. The genetic algorithm is used to obtain the solutions to the rescue resources dispatching model. A case study shows that the proposed method can accurately reveal the impact of potential incidents on the costs of rescues according to the variations in the types and quantities of rescue resources and the optimal dispatching plan with respect to potential incidents can be obtained.The proposed method is applicable in real world scenarios.