Objective To investigate the clinical significance for hollow needle aspiration in breast cancer diagnosis.Method Aspiration was conducted in 47 cases of breast tumors of size 1.8cm to 5.0cm using fine needle and 14G hollow needle.Result The result of fine needle aspiration cytology showed that breast cancer was diagnosed in 15 cases,12 cases were suspicious,and 20 cases were indefinite.The result of hollow needle aspiration pathology showed that 32 cases(68%) had moderate-differentiated infiltrating duct-carcinoma,8 cases(17%) had poor-differentiated infiltrating duct-carcinoma,2 cases had medullar carcinoma medullar carcinoma,5 cases had benign lesion?Conclusion The accuracy rate of hollow needle aspiration pathology is very high,because it gets a lot of tissue.
目的观察参芪扶正注射液配合化疗使用对Ⅳ期乳腺癌患者血清CA 153水平及免疫细胞活性的影响,并评价其临床意义。方法将60例经病理确诊的Ⅳ期乳腺癌患者分为治疗组(长春瑞滨+5-FU+参芪扶正注射液)及对照组(长春瑞滨+5-FU),于治疗前1天及治疗4周期后各采外周静脉血4 m l,用免疫放射分析法(R IM A)检测血清CA 153水平,用流式细胞术检测T细胞亚群和NK细胞活性。结果治疗后两组患者的血清CA 153水平均较治疗前显著下降(P<0.05),但参芪扶正注射液治疗组较对照组下降幅度更大(P<0.05);化疗后对照组患者T细胞亚群的活性均下降(P<0.05),而治疗组仅CD 3显著下降(P<0.05);化疗后治疗组患者NK细胞活性未受影响(P>0.05),但对照组NK细胞活性显著下降(P<0.05)。结论参芪扶正注射液能提高晚期乳腺癌患者机体免疫细胞(T细胞亚群/NK细胞)的活性;能协同化疗降低晚期乳腺癌患者血清CA 153水平。
