To find out the effect of scan rate on sensitivity in quadrupole mass spectrometer,DDV and 11 common hypnotic drugs were chosen for GC-MS analysis.Different scan time and dwell time was used separately for full scan mode and SIM.Then charasteristic ions were extracted to calculate signal to noise values.
Using quadrupole mass spectrometer,calibration gas PFTBA was turned on in constant flow to get the signal intensity,and off to get the noise value.Different scan time and dwell time was used separately for full scan mode and SIM to find out the effect of scan rate on signal intensity and noise.