The work address the problem of modeling the dynamical oscillating behavior during both unstable and stable operations, of an experimental thermosyphon. A standard RBF artificial neural network-based prediction model was developed for predicting the oscillating heat transfer of thermosyphon by means of input-output experimental measurements with the characteristics of time series. A comparison of prediction values between the RBF network and the MLP network was giving.The precision of RBF network was higher than that of the other neural networks such as BP-MLP network etc . The dynamical model of RBF network could be used to describe, predict and control the heat transfer process of a thermosyphon or a heat pipe system.