Three-dimensional velocity images of the crust and upper mantlebeneath orogenic belts and adjacent basins of the northwestern continent of China are reconstructed by seismic tomography, based on arrival data of P wave recorded in seismic networks in Xinjiang, Qinghai, Gansu of China and Kyrgyzstan. The velocity images of upper crust demonstrate the tectonic framework on the ground surface. High velocities are observed beneath orogenic belts, and low velocities are observed in the basins and depressions that are obviously related to unconsolidated sediments. The velocity image in mid-crust maintains the above features, and in addition low velocities appear in some earthquake regions and a low velocity boundary separates the western Tianshan Mts. from eastern Tianshan Mts. The orogenic belts and the northern Tibetan plateau have a Moho depth over 50 km, whereas the depths of the Moho in basins and depressions are smaller than 50 km. The velocity images of upper mantle clearly reveal the colliding relationship and location of deep boundaries of the continental blocks in northwestern China, indicating a weakness of the upper mantle structure of orogenic belts. The top depth of upper mantle asthenosphere varies from place to place. It seems shallower under the northern Tibetan plateau, Altay and Qilian Mts., and deeper under the Tarim and Tianshan regions. Hot mantle probably rose to the bottom of some orogenic belts along tectonic boundaries when continental blocks collided to each other. Therefore their dynamic features are closely correlated to the formation and evolution of orogenic belts in northwestern China.