Chiral spirocyclic phosphoric acids(SPAs)are introduced in 2010 and have been versatile catalysts capable of promoting a wide range of asymmetric organocatalytic reactions,such as multi-component reactions,Friedel–Crafts reactions,Pictet–Spengler reactions,Fischer indolizations,cycloaddition reactions,desymmetrization reactions,dearomatization reactions,conjugate addition reactions and rearrangement reactions,etc.Moreover,a diverse range of applications in metal-organic cooperative catalysis,organic photoredox catalysis,total synthesis,materials science and molecular recognition are beautifully illustrated.This account summarizes the past decade's advances in this field and highlights the selected but not comprehensive significant achievements.
