Previously Fourier transform infrared（FTIR） spectroscopy has been applied to detecting thyroid cancer during operations and to discriminating cervical metastatic ones from non-metastatic lymph nodes. This study explored the possibility of establishing a sensitive, accurate and noninvasive screen or diagnosis by preoperative FTIR spectroscopy. 111 patients undergone a thyroid operation and 50 healthy volunteers were enrolled in the study. The FTIR spectra were obtained by two mid-infrared optical fibers with an attenuated total reflectance（ATR） probe closely contacting the subjects＇ skin on the thyroid nodules. The FTIR spectra obtained from normal thyroid, nodular goiter（NG） and papillary thyroid carcinoma（PTC） patients were compared. A Fisher＇s discriminant analysis was created based on these data. There were 41 PTC patients and 70 NG patients according to their histopathological examinations. A total of 23（of 39） parameters were statistically different among the three groups（P〈0.05）. The Fi300 and F1080 parameters were significantly different between the three groups. In total, 9 out of 39 FTIR parameters were selected as independent factors by the Wilks＇ lambda stepwise discriminant analysis. The discrimination accuracy of papillary thyroid carcinoma in the three groups was 88.8%. Surface detection of PTC by FTIR spectroscopy is feasible. FTIR spectroscopy can be used for rapid and noninvasive PTC screen and auxiliary diagnosis.
Two dimensional asynchronous spectra were used to characterize coordination between carbonyl group of butanone and metal ions by using an approach proposed in our recent paper.Spectral variation of n-π^＊transition band of carbonyl group is used to probe the coordination even if metal ions does not possess any characteristic peak in spectra.Experimental results indicate that Ca^2＋ and Al^3＋ show considerable ability to coordinate with the carbonyl group of butanone and bring about spectral variation of the n-π-＊transition band,which is manifested by cross peaks in 2D asynchronous spectra.
In this paper,2D asynchronous spectra generated by using the DAOSD approach was utilized to probe interactions between Nd^3＋ and pyridinium dissolved in aqueous solution.A series of cross peaks in the resultant 2D asynchronous spectrum confirms the occurrence of intermolecular interaction between Nd^3＋and pyridinium.However,no coordination occurs between Nd^3＋ and pyridinium.Interaction between πelectron from aromatic system and/electron from lanthanide ions account for the appearance of cross peaks in 2D asynchronous spectra.Because of the interaction,the emission spectrum of pyridinium exhibits a significant change when neodymium perchlorate was introduced into the system.
A Keggin-type polyoxomolybdate[H2biim]{Ni（biim）3（SiMO12O40）}[biim =1H,1＇H-[2,2＇]biimidazolyl]has been synthesized under hydrothermal condition and characterized by XRD,temperature-dependent IR,TG,temperature-induced and magnetism-induced 2D infrared correlation spectroscopy（2D-IR COS）and UV-vis DRS in order to explore the relationship between structure and properties.Temperatureinduced 2D-IR COS spectroscopy indicates that the terminal Mo-Oμ/υbonds are more sensitive than the bridging Mo=Ot,bands to temperature variation,which is in agreement with the conclusion of temperature-dependent IR.Magnetism-dependent 2D-IR COS spectroscopy reveals the stretching vibration of the Mo=Ot,occurs prior to the stretching vibration of the Mo-Oμ/υ,which is due to the coordination environment and the valence of the Si atom.The stability of compound 1 is investigated via TG and temperature-dependent IR.In RhB degradation,compound 1 shows good photocatalytic abilities.
Hao WangYi-Ping ChenZhu-Chai YouMeng-Xi ZhouNing ZhangYan-Qiong Sun
