On the basis of Space-Wise Least Square method, three numerical methods including Cholesky de- composition, pre-conditioned conjugate gradient and Open Multi-Processing parallel algorithm are applied into the determination of gravity field with satellite gravity gradiometry data. The results show that, Cholesky de- composition method has been unable to meet the requirements of computation efficiency when the computer hardware is limited. Pre-conditioned conjugate gradient method can improve the computation efficiency of huge matrix inversion, but it also brings a certain loss of precision. The application of Open Multi-Processing parallel algorithm could achieve a good compromise between accuracy and computation efficiency.