The enantioselective reduction of acetophenone analogues catalyzed by carrot and celeriac was performed in moderate conversions and excellent enantiomeric excesses.The steric factors and electronic effects of the substituents at the aromatic ring were found to significantly affect the efficiency of the enantioselective reduction of acetophenone analogues,while they had a little effect on the enantioselectivity of acetophenone analogues reduction.It was also found that the conversions of acetophenone analogu...
A reaction of α-bromo aromatic ketones in water with microwave irradiation gave the corresponding α-hydroxy aromatic ketones in good yields. The use of microwaves was found to significantly improve yields and shorten the reaction time. This reaction afforded a very clean, convenient method for the synthesis of α-hydroxy aromatic ketones.
Xiang LiuHai Bo ChenZheng Guang PanJian He XuHe Xing Li
