Dynamic nuclear polarization(DNP) has become a very important hyperpolarization method because it can dramatically increase the sensitivity of nuclear magnetic resonance(NMR) of various molecules.Liquid-state DNP based on Overhauser effect is capable of directly enhancing polarization of all kinds of nuclei in the system.The combination of simultaneous Overhauser multi-nuclei enhancements with the multi-nuclei parallel acquisitions provides a variety of important applications in both MR spectroscopy(MRS) and image(MRI).Here we present two simple illustrative examples for simultaneously enhanced multi-nuclear spectra and images to demonstrate the principle and superiority.We have observed very large simultaneous DNP enhancements for different nuclei,such as ~1H and ^(23)Na,~1H and ^(31)P,^(19)F and ^(31)P,especially for the first time to report sodium ion enhancement in liquid.We have also obtained the simultaneous images of ^(19)H and ^(31)P,^(19)F and ^(31)P at low field by solution-state DNP for the first time.
Yugui HeZhen ZhangJiwen FengChongyang HuangFang ChenChaoyang LiuMaili Liu
