Sampling from a truncated multivariate normal distribution (TMVND) constitutes the core computational module in fitting many statistical and econometric models. We propose two efficient methods, an iterative data augmentation (DA) algorithm and a non-iterative inverse Bayes formulae (IBF) sampler, to simulate TMVND and generalize them to multivariate normal distributions with linear inequality constraints. By creating a Bayesian incomplete-data structure, the posterior step of the DA Mgorithm directly generates random vector draws as opposed to single element draws, resulting obvious computational advantage and easy coding with common statistical software packages such as S-PLUS, MATLAB and GAUSS. Furthermore, the DA provides a ready structure for implementing a fast EM algorithm to identify the mode of TMVND, which has many potential applications in statistical inference of constrained parameter problems. In addition, utilizing this mode as an intermediate result, the IBF sampling provides a novel alternative to Gibbs sampling and elimi- nares problems with convergence and possible slow convergence due to the high correlation between components of a TMVND. The DA algorithm is applied to a linear regression model with constrained parameters and is illustrated with a published data set. Numerical comparisons show that the proposed DA algorithm and IBF sampler are more efficient than the Gibbs sampler and the accept-reject algorithm.