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国家自然科学基金(81001228)

作品数:3 被引量:27H指数:2
相关作者:储晨桂永浩更多>>
相关机构:复旦大学更多>>
发文基金:国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划更多>>
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Diurnal Temperature Range as a Novel Risk Factor for Sudden Infant Death
2011年
Objective To assess the relationship between diurnal temperature range (DTR) and sudden infant death (SID) between 2001 and 2004 in Shanghai,China.Methods We conducted a time‐stratified case‐crossover analysis to estimate the percent increase of SID associated with changes in DTR after adjustment for daily weather conditions (temperature and relative humidity) and outdoor air pollution.Results DTR was significantly associated with daily SID.An increase of 1 °C in the current‐day (L0) and in the 2‐day moving average (L01) DTR corresponds to a 1.56% (95% CI:0.97%,2.15%) and a 1.89% (95% CI:1.17%,2.60%) increase in SID,respectively.Conclusion An increased DTR was associated with an increased risk of SID in Shanghai.More studies are needed to understand the effect of DTR on infant deaths.
CHU ChenZHOU WenHaoGUI YongHaoKAN HaiDong
关键词:婴儿猝死SID空气污染
The Impacts of Maternal Gestational Diabetes Mellitus (GDM) on Fetal Hearts被引量:20
2012年
Objective To evaluate the fetal cardiac function in gestational diabetes mellitus (GDM) pregnancies under different maternal glycemic controls.Methods Forty four GDM mothers received 78 fetal echocardiographic evaluations at three gestational periods (<28,28-34 and ≥34 weeks) and were divided into poorly-(DM1) and well-(DM2) controlled groups according to their glycemic control at examination.Seventy uncomplicated mothers were selected as controls.Parameters of fetal cardiac anatomy and function were measured and analyzed.Results GDM fetuses' cardiac ventricular walls were thicker than controls',and the differences between DM1 and DM2 were not significant except for end-diastolic left ventricular walls.In both GDM groups,the aortic flow velocities increased earlier than pulmonary artery and DM1 fetuses changed earlier than DM2 ones.GDM fetuses' left atrial shortening fraction was smaller than the controls' in the period of ≥34 weeks and negatively correlated with thicknesses of left ventricular walls and interventricular septum in DM1 fetuses (r=-0.438 and -0.506).The right ventricular diastolic function in DM1 and DM2 fetuses decreased after the period of 28-34 weeks and in the period of ≥34 weeks respectively.Tei index of both left and right ventricles increased in DM1 group after the period of<28 weeks and in DM2 group only in the period of ≥34 weeks,with no significant differences between DM1 and DM2 groups in this period.Conclusion Fetuses of GDM mothers showed cardiac function impairments.Good maternal glycemic control may delay the impairments,but cannot reduce the degree.Some cardiac changes in GDM fetuses were similar to those in pregestational diabetic pregnancies except for several parameters and their changing time.
CHU ChenGUI Yong HaoPEN Yun YunSHI Li Ye
关键词:心脏功能超声心动图DM2
先天性心脏病产前诊断对围产儿结局的影响被引量:7
2014年
先天性心脏病(简称先心病)是最常见、也是最严重的先天性畸形之一.据统计,中国先天性畸形的发病率近1 5年来增长了70%,其中先心病的发病率为近年来最高[1].中国出生缺陷防治报告显示,2011年全国出生缺陷监测系统统计的围产期先心病发病率达到了40.95/10 000[2].先心病居我国5岁以下儿童死亡原因的第4位和先天性畸形的首位[1].白20世纪80年代以来,超声心动图作为产前诊断先心病最主要和最关键的技术已经在临床广泛应用.超声心动图不仅可以诊断胎儿心脏结构异常,还可检测并定性心律失常,评价胎儿心脏功能。
储晨桂永浩
关键词:先天性心脏病产前诊断胎儿心脏功能先天性畸形超声心动图心脏结构异常
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