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国家自然科学基金(91130005)

作品数:5 被引量:5H指数:1
相关作者:李方廷更多>>
相关机构:北京大学北京大学第三医院更多>>
发文基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Well-posedness for the stochastic 2D primitive equations with Lévy noise被引量:1
2013年
The two-dimensional primitive equations with Lévy noise are studied in this paper.We prove the existence and uniqueness of the solutions in a fixed probability space which based on a priori estimates,weak convergence method and monotonicity arguments.
SUN ChengFengGAO HongJun
关键词:适定性先验估计弱收敛
Exponential convergence of the deep neural network approximation for analytic functions Dedicated to Professor Ta Tsien Li on the Occasion of His 80th Birthday被引量:4
2018年
We prove that for analytic functions in low dimension, the convergence rate of the deep neural network approximation is exponential.
Weinan EQingcan Wang
关键词:TA集中率
Mean field limit of a dynamical model of polymer systems
2013年
This paper provides a mathematically rigorous foundation for self-consistent mean feld theory of the polymeric physics.We study a new model for dynamics of mono-polymer systems.Every polymer is regarded as a string of points which are moving randomly as Brownian motions and under elastic forces.Every two points on the same string or on two diferent strings also interact under a pairwise potential V.The dynamics of the system is described by a system of N coupled stochastic partial diferential equations(SPDEs).We show that the mean feld limit as N→∞of the system is a self-consistent McKean-Vlasov type equation,under suitable assumptions on the initial and boundary conditions and regularity of V.We also prove that both the SPDE system of the polymers and the mean feld limit equation are well-posed.
E WeinanSHEN Hao
关键词:随机偏微分方程平均场理论系统动力学生日
Non-equilibrium and stochasticity influence the activation process of the yeast DNA damage pathway
2018年
Living cells are open systems that exist far away from a state of thermodynamical equilibrium.They utilize the high-grade chemical energy provided by food to produce ATP and release ADP and Pi together with heat dissipation.Living cells exist in a non-equilibrium steady state(NESS),they replicate themselves and respond to various environmental changes
ChenZi JinXiaoDong YanFangTing Li
前列腺癌的演化动力学模型以及治疗策略的优化
2019年
前列腺癌是男性常见的恶性肿瘤。临床上常用的干扰雄激素的治疗药物是阿比特龙,但长期高剂量的阿比特龙治疗常导致患者前列腺肿瘤细胞进化至药物抵抗。为了揭示前列腺癌发展的动力学机制,本文引入给药剂量因素,建立二变量的肿瘤演化定量模型。通过分析固定给药和适应性给药策略的动力学性质,并绘制势能景观图,从动力学角度展示适应性给药策略的优势,揭示高剂量药物导致体系演化为不可逆药物抵抗状态的动力学机理。此外还构建治疗策略的评分体系,以便优化治疗策略。
高鑫史书毓李方廷
关键词:前列腺癌药物抵抗动力学模型
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