Pyrophosphate ion(PO,PPi) is known to be one crucial anion not only because of its important role in a wide ra...
Li Jiao Liang~(a,b),Cheng Zhi Huang~(a,c*) (a Education Ministry Key Laboratory on Luminescence and Real-Time Analysis,College of Chemistry and Chemical Engineering,Southwest University b,School of Chemistry and Environmental Engineering, Chongqing Three Gorges University c,College of Pharmaceutical Sciences,Southwest University, Chongqing,400715,PR China.)
Homochirality in life has always been a driving force in scientific research and natural exploration. It has not been satisfactorily explained, and systematic investigations are necessary. This paper reported a homochiral expression of proteins dependent on the stirring direction of growing media. By controlling the stirring direction clockwise (CW) and anticlockwise (ACW) of the culture medium, proteins with distinct secondary structures were obtained, and D-amino acid may be included in the protein cultured with the stirring direction of ACW. Considering the effect of force fields, which might affect the process of folding and refolding of cellular protein in this report, the control of force fields might be a good way to prepare asymmetric drugs, and the rotational direction of the earth is possibly related to the chirality in primitive life molecules.
HU PingPing1,2, PENG Li2, ZHEN ShuJun3, CHEN LiQiang2, XIAO SaiJin1 & HUANG ChengZhi1,3 1Key Laboratory on Luminescence Real-Time Analysis, Ministry of Education
In this study,a spectrophotometric detection method for diethylstilbestrol(DES)was proposed by reducing silver nitrate(AgNO3)to obtain silver nanoparticles(AgNPs)in the medium of ammonia and sodium hydroxide.It was found that the resulting AgNPs have plasmon resonance absorption(PRA)characteristic at 415 nm,and the PRA is proportional to the increase of DES concentration in the range of 4.0×10-8-1.0×10-5M with the detection limit(3σ)of 1.2×10-7M.Most of the coexisting substances at high concentrations did not affect the detection of real samples,such as tablets.The recovery was in the range of 96.01%-107.41% and the RSD was lower than 4.7%.This method can be successfully applied to control preparation quality of DES.
Lin He,Cheng-Zhi HuangEducation Ministry Key Laboratory on Luminescence and Real-Time Analysis,College of Pharmaceutical Science,Southwest University,Chongqing 400715,China
