In this paper, we study an important class of (α,β)-metrics in the form F = (α + β)m+1/αm on an n-dimensional manifold and get the conditions for such metrics to be weakly-Berwald metrics, where α = aij(x)yiyj is a Riemannian metric and β = bi(x)yi is a 1-form and m is a real number with m = 1,0,1/n. Furthermore, we also prove that this kind of (α,β)-metrics is of isotropic mean Berwald curvature if and only if it is of isotropic S-curvature. In this case, S-curvature vanishes and the metric is weakly-Berwald metric.