Glycyrrhizic acid-Cu(Ⅱ) and glycyrrhizic acidFe(Ⅲ)complexes were synthesized by solution-phase synthesis.The complexes were characterized by elemental analysis,FTIR and UV-Vis spectra analysis.The antioxidant activity of glycyrrhizic acid and its complexes was studied.The experimental results show that glycyrrhizic acid and its Cu(Ⅱ) and Fe(Ⅲ) complexes have an excellent elimination ability to O2-·.However,the antioxidant activity of glycyrrhizic acid is better.