In this paper,an unreported novel acylpyrazolone——1-(p-Cl-phenyl)-3-phenyl-4-benzoyl-pyrazolone-5(CPPBP) and its five Schiff bases have been synthesized in the nonaqueous solvent.Their molecular structures are characterized by the elemental analysis,IR,MS and 1H NMR and an elementary antibacterial activity experiment is made.The results of structural characterization show that CPPBP exist in ketoform structure mainly and other five compounds S1,S2,S3,S4 and S5 coexisted in ketoform and enolform structure after forming the schiff bases.The antibacterial avtivity experiment indicat that six compounds are resistant to four different bacteria with various degrees.
In this paper,one novel Schiff base(HL) derived from 1-phenyl-3-methyl-4-benzoyl-pyrazolone-5(PMBP) and sulfanilamide and its corresponding transitional metallic copper complex have been synthesized in the nonaqueous solvent.The formula of complex is CuL2 based on elemental analysis,complexometric titration,molar conductance value and mass spectra data.Its molecular structure is characterized by means of IR,TG and 1HNMR,etc.,and the antibacterial activities under different concentrations of these two compounds are also measured with Oxford cup method.
