The concentrations of 16 phthalates in 164 commercial Chinese rice wines （CRW） were detected by GC-MS, and consumption data on CRW in different packaging types was investigated from 634 adult males in Shanghai using a food frequency questionnaire. Based on the prinq：iples of probabilistic modelling and cumulative risk assessment, the exposure and health risk of phthalates from CRW to adult males in Shanghai was evaluated. DMP, DEP, DIBP, DnBP, BBP, and DEHP were detected in the samples, thE： range of detection frequency of individual phthalates varied from 6.10% for BBP to 15.24% for DIBP, and the detected concentrations were 51.06-200.34 ng/mL. All the respondents consumed CRW, 90.69% of them consumed CRW 0.01-49.9 mL/d, the minimum value of the average daily intake of CRW was 6.25 mL/d, the median was 13.72 mL/d and the maximum was 300 mL/d. The median exposure level of the 6 detected Phthalates to adult males in Shanghai were 6.58-7.10 ng/（d.kg）, and the maximum exposure level were 137.38-540.47 ng/（d.kg）. The cumulative exposure health risk index （HI） based on the median and maximum exposure level of the 6 Phthalates （DMP, I~）EP, DIBP, DnBP, BBP, and DEHP） were 0.001147 ancl 0.063396, both were far less than 1. In conclusion, CRW were generally consumed by the adult males in Shanghai.
HUANG YueLU Wen WeiCHEN BoYOU JieWU MinLI Shu Guang
[目的]建立人尿中的三聚氰胺液相色谱-串联质谱测定法。[方法]尿样经0.2 mol/L盐酸酸化,乙腈超声提取,MCX固相萃取柱净化及浓缩后,10μL进样,并用液相色谱-串联质谱仪进行检测,检测的色谱条件为：色谱柱为CAPCELL PAK CR SCX∶C18=1∶4,流动相为10 mmol/L的乙酸铵-乙腈-0.1%甲酸混和溶液（体积分数40∶50∶10）,柱温为30℃,流速为0.2 m L/min。[结果]三聚氰胺的保留时间3.95min,三聚氰胺在5~200μg/L的浓度范围内呈线性关系,R2为0.999 8。浓度在10、50、100μg/L时,回收率在96.7%~97.2%范围内,相对标准偏差≤5.16%,最低检出限为0.6μg/L,最低定量限为2μg/L。[结论]该方法前处理简便,灵敏度高,适合用来检测人尿液中三聚氰胺。
