The first synthesis of the naturally occurring cyclic peptide euryjanicin B has been achieved.A general method was described to synthesize the cyclic peptide by a two-step solid-phase/solution synthesis strategy.All the amino acids in this study are L-configuration. The linear heptapeptide was assembled by standard Fmoc chemistry on solid-phase and subsequently cyclization was carried out by solution method.
Chun Mei ZhangJun Xiang GuoLiang WangXiao Yun ChaiHong Gang HuQiu Ye Wu
